Frequency and species distribution of Candida in oral cavity of human immunodeficiency virus-infected patients

Objective The evaluate the status of colonization of Candida in oral cavity of human immunodeficiency virus(HIV)-infected patients.Methods Oral rinses in 82 patients(49 male and 33 female) with HIV infection were collected and detected by morphologic observation,the API 20 C AUX yeast identification system,and growth test at 45℃,and the frequency of Candida infection was calculated.Results Out of 82 patients,Candida was isolated from 60 patients(73.17%),of which 42 patients(51.22%) with Candida albicans infection,48 patients(58.54%) with non-albicans species infection.There were 211 strains of Candida were isolated,of which 103 strains were Candida glabrata(48.82%),95 strains were Candida albicans(45.02%),4 strains were Candida tropicalis(1.90%),4 strains were Candida parapsilosis(1.90%),2 strains were Candida pelliculosa(0.95%),and 3 strains were other Candidas(1.42%).There were 29 patients with single Candida infection(48.33%) while 31 patients with multiple Candida infection(51.67%).Conclusion Candida glabrata and Candida albicans were the main Candida isolated from oral cavity of HIV-infected patients,and frequency of coexisted situation of them were higher than that of single infection of them.