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2008•Journal of Medical ForumRequires access

Effects of Micronised Fenofibrate on Hyperlipidemia and CsA Concentration in Kidney Transplantation Recipients

Youhua Zhu

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Abstract

Objective To observe the influence of fenofibrate on hyperlipidemia and CsA concentration and uric acid in kidney transplantation.Methods Total 56 hyperlipidemic cases were treated 200mg/d fenofibrate for one month,then analyzed concentrations of serum lipids and CsA,etc.Results Treatment with fenofibrate for one month led to marked reduction in serum TG and T-CHOL,uric acid,the reduction of TG was more obvious.While change of LDL had no statistics' means.At the same time serum HDL was increased.Concentration of CsA was unchanged.Conclusion Treatment with fenofibrate can decrease hyperlipidemia and uric acid in kidney transplantation recipients,and CsA concentration was unaffected.

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What this paper is about

Objective To observe the influence of fenofibrate on hyperlipidemia and CsA concentration and uric acid in kidney transplantation.Methods Total 56 hyperlipidemic cases were treated 200mg/d fenofibrate for one month,then analyzed concentrations of serum lipids and CsA,etc.Results Treatment with fenofibrate for one month led to marked reduction in serum TG and T-CHOL,uric acid,the reduction of TG was more obvious.While change of LDL had no statistics' means.At the same time serum HDL was increased.Concentration of CsA was unchanged.Conclusion Treatment with fenofibrate can decrease hyperlipidemia and uric acid in kidney transplantation recipients,and CsA concentration was unaffected.

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Available abstract

Objective To observe the influence of fenofibrate on hyperlipidemia and CsA concentration and uric acid in kidney transplantation.Methods Total 56 hyperlipidemic cases were treated 200mg/d fenofibrate for one month,then analyzed concentrations of serum lipids and CsA,etc.Results Treatment with fenofibrate for one month led to marked reduction in serum TG and T-CHOL,uric acid,the reduction of TG was more obvious.While change of LDL had no statistics' means.At the same time serum HDL was increased.Concentration of CsA was unchanged.Conclusion Treatment with fenofibrate can decrease hyperlipidemia and uric acid in kidney transplantation recipients,and CsA concentration was unaffected.

Key concepts: Fenofibrate, Hyperlipidemia, Uric acid, Internal medicine, Medicine, Transplantation, Kidney, Endocrinology

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Effects of Micronised Fenofibrate on Hyperlipidemia and CsA Concentration in Kidney Transplantation Recipients — Research Paper | ScholarLens