Progress in study of potassium channels in human cardiomyocytes

Potassium channels which are targets of antiarrhythmic drugs (class III) play an important role in cardiomyocyte membrane. Recently, with the application of molecular biology techniques , development of cloned potassium channels, successful isolation of human cardiomyocytes and research of single channel, scientists have learnedmore characteristics of kinetics, electrophysiology and pharmacology of potassium channels. All these help them to develop and study new antiarrhythmic drugs.