The clinical observation of matoprolol combined digoxin in the treatment of heart failure patients with atrial fibrillation

Objective To observe the efficiency and safety on low-dose metoprolol combined with digoxin in the treatment of heart failure with rapid atrial fibrillation.Methods Sixty patients with atrial fibrillation and organic heart disease were randomly divided into the treatment group ( n = 30) and the control group ( n = 30) , the control group were treated by the conventional diuresis, blood vessel dilatation medicine and digoxin, the treatment group were treated by small dosage metoprolol treatment on the foundation of above treatment, and after three months, the data of two groups of patients were compared and analysed on cardiac function, ventricular rate and left ventricular ejection fraction (LVEF).Results The treatment group was better than the control group on reducing ventricle rate, improving cardiac function and enhancing LVEF ( P 0.05 ).Conclusion Small dosage metoprolol combined the digoxin can safely, efficiently reduce ventricular vate and improve cardiac function in patients with heart failure and rapid atrial fibrillation.