The clinical trial on the treatment of pediatric peptic ulcer.

【Objectives】 To observe the effect of different therapy in the management of peptic ulcer and the eradicative rate Helicobacter pylori. 【Methods】 80 patients with pediatric Helicobacter pylori peptic ulcer were divided into 2 groups.Group A was treated with Omeprazole 0.8mg/(kg·d) for 2 weeks,group B with CBS 8 mg/(kg·d) for 2 weeks.Amoxycillin 50 mg/(kg·d) and metronidazol were admindstered to all the groups. 【Results】 91.67%(44/48) of peptic ulcer in group A,75.00%(24/32) in group B.83.33%(40/48) of Helicobacter pylori in group A,56.25%(18/32) in group B were eradicated.96.56% of the peptic ulcer were cured in patients Helicobacter pylori eradicated,while 54.55% in uneradicated. 【Conclusion】 Proton pump inhibitor(Omeprazole) in combination with antibiotics is showed more efficient therapeutic effect.Helicobacter pylori eradication can improve the pediatric peptic ulcer cure rate.