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Research Advances on Type 1 Pilus of Uropathogenic Escherichia coli

Li L

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Abstract

Urinary tract infections are serious public health problem worldwide.Strains of uropathogenic Escherichia coli(UPEC)are the primary cause of urinary tract infections.Type 1 pilus of UPEC is a very important virulence factor,widely distributed in UPEC,and mediates its adhesion,invasion and colonization in the urinary tract.The structure,assembly and virulence mechanism of type 1 pilus were reviewed in this paper.

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What this paper is about

Urinary tract infections are serious public health problem worldwide.Strains of uropathogenic Escherichia coli(UPEC)are the primary cause of urinary tract infections.Type 1 pilus of UPEC is a very important virulence factor,widely distributed in UPEC,and mediates its adhesion,invasion and colonization in the urinary tract.The structure,assembly and virulence mechanism of type 1 pilus were reviewed in this paper.

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Available abstract

Urinary tract infections are serious public health problem worldwide.Strains of uropathogenic Escherichia coli(UPEC)are the primary cause of urinary tract infections.Type 1 pilus of UPEC is a very important virulence factor,widely distributed in UPEC,and mediates its adhesion,invasion and colonization in the urinary tract.The structure,assembly and virulence mechanism of type 1 pilus were reviewed in this paper.

Key concepts: Pilus, Virulence, Microbiology, Escherichia coli, Urinary system, Fimbria, Virulence factor, Medicine

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