Research Advances on Type 1 Pilus of Uropathogenic Escherichia coli
Li L
Abstract
Li L
Abstract
Urinary tract infections are serious public health problem worldwide.Strains of uropathogenic Escherichia coli(UPEC)are the primary cause of urinary tract infections.Type 1 pilus of UPEC is a very important virulence factor,widely distributed in UPEC,and mediates its adhesion,invasion and colonization in the urinary tract.The structure,assembly and virulence mechanism of type 1 pilus were reviewed in this paper.
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Urinary tract infections are serious public health problem worldwide.Strains of uropathogenic Escherichia coli(UPEC)are the primary cause of urinary tract infections.Type 1 pilus of UPEC is a very important virulence factor,widely distributed in UPEC,and mediates its adhesion,invasion and colonization in the urinary tract.The structure,assembly and virulence mechanism of type 1 pilus were reviewed in this paper.
Key concepts: Pilus, Virulence, Microbiology, Escherichia coli, Urinary system, Fimbria, Virulence factor, Medicine