Monitoring on Immune Successful Rate of Measles Vaccine and Measles-Mumps-Rubella Vaccine in Jiangsu

Objective To know the immunogenicity of measles vaccine and measles-mumps-rubella vaccine after expanded program on immunization,and to provide a basis for elimination of measles and control of mumps and rubella. Methods The sera samples of 120 8-month-old infants and 117 children aged from 18 to 24 months were collected before and 4 weeks after immunization of measles vaccine and measles-mumps-rubella vaccine,respectively.Then the antibodies were determined. Results The circulating measles antibody acquired from mother in 8-month-old infants disappeared.The positive rate of antibody to measles after immunization of measles vaccine was 100%.The positive rate of antibody to measles in 117 children aged from 18 to 24 months was 99.15%,but it was 100% after revaccination with MMR vaccine.The average content of antibody to measles in the 117 children was 5,077.11 mIU/ml,but it was 14,410.57 mIU/ml after revaccination with MMR vaccine.The positive rates of antibodies to mumps and rubella were 93.91% and 96.46%,respectively. Conclusions The immunogenicity of measles vaccine is good.The current measles vaccine,the program and the dose are feasible and effective.Revaccination with MMR vaccine is significant in remarkably increasing the antibody to measles and effectively protecting children from measles,mumps and rubella.