Changes and Clinical Significance of the Concentration of Serum Zinc and Plumbum in Children with Complex Febrile Convulsion

Objective:To study the changes and clinical significance of the concentration of serum zinc and plumbum in children with complex febrile convulsion(FC). Methods: We divided 38 cases of febrile convulsion admitted the hospital into complex febrile convulsion groups and simple febrile convulsion groups by clinical manifestation during August 2006 to May 2007. While 50 healthy children were chosen as the control groups by randomized. The concentration of serum zinc and plumbum were measured and analyzed for each of the 88 children. Results: The concentration of serum zinc descended in order of the groups of the healthy, the simple febrile convulsion and complex febrile convulsion. Analysis of variance showed,while significances among the simple febrile convulsion groups and complex febrile convulsion groups (P 0.05). The concentration of serum plum-bum ascended in order of the groups of the healthy, the simple febrile convulsion and complex febrile convulsion. Analysis of variance showed statistical significances among the three groups (P 0.05). Conclusion: The concentration of serum zinc descended, while the concentration of serum plumbum ascended in patients with FC. Hence, studying the relation between febrile convulsion and trace elements could have a unique significance to the prevention and treatment of febrile convulsion.