Application of contrast-enhanced ultrasonography used in qualitative diagnosis of regenerative nodules in cirrhotic liver

Objective To analysis the application of contrast-enhanced ultrasonography used in qualitative diagnosis of regenerative nodules in cirrhotic liver.Methods Contrast-enhanced ultrasonography was performed on 32 patients with SRNs which had pathologic diagnosis from biopsy.The enhancement pattern was analyzed by time-intensity curves,then the diagnostic accuracy of CEUS was compared with conventional ultrasound.Results The enhancement patterns were classified as the following 4 types: Type I enhanced simultaneously and presented the isoecho with the liver(26/46);Type Ⅱ slow-in and become the isoecho in parenchymal phase(16/46);Type Ⅲfast-in and slow-out(3/46);Type Ⅳ enhancement(1/46).Slope of upslope and decent,average intensity in SRNs had significant deviation with liver parenchyma.Time-to-peak had no significant deviation with no liver parenchyma.The diagnostic accuracy of conventional sonography was 65.79%,the diagnostic accuracy of CEUS was 88.37%.Conclusion The diagnostic accuracy of CEUS is superior to conventional sonography,it can evaluate the vascularization in SRNs effectively,especially SRNs that conventional sonography can not find.CEUS is important for SRNs that are malignant tentatively.