2013Laboratory Medicine and ClinicRequires access

Analysis on the allergens of children with allergic diseases in 350 cases

Jiansheng Lin

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Abstract

Objective To detect specificity serum IgE antibody from children with allergic diseases,then to screen related allergens in order to provide a scientific evidence in the diagnosis and treatment of children with allergic diseases.Methods The specificity serum IgE antibody of 350 children with allergic diseases were detected quantitatively by allergy screen allergens test system.Results The positive rate of 14 kinds of allergens in 350 children with allergic diseases was 57.71%.Among the 14 kinds of allergens,the amount of children with positive dust mites was the highest,followed by milk and cat fur,dog fur and chicken egg protein.Cockroaches,mould,beef and mutton also took a rather high ratio of it.There was no significant difference in the positive rate of allergens between boys and girls(P0.05).In inhalant allergen group,the positive rate of allergens in pre-school children and school-age children were all significantly higher than that of infants(P0.05).In food allergen group,the positive rate of allergens in infants was significantly higher than that in pre-school children and school-age children(P0.05).Among the infants,the positive rate of allergens in food allergen group was significantly higher than that in inhalant allergen group(P0.05);Among the pre-school children and school-age children,the positive rates of allergens in inhalant allergen group were all significantly higher than that in food allergen group(P0.01).Conclusion The main allergen in Quanzhou region is dust mite,followed by milk and cat fur,dog fur and chicken egg protein;There is no significant difference of the positive rate of allergens between boys and girls.The children at different ages have different compositions of allergens.

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What this paper is about

Objective To detect specificity serum IgE antibody from children with allergic diseases,then to screen related allergens in order to provide a scientific evidence in the diagnosis and treatment of children with allergic diseases.Methods The specificity serum IgE antibody of 350 children with allergic diseases were detected quantitatively by allergy screen allergens test system.Results The positive rate of 14 kinds of allergens in 350 children with allergic diseases was 57.71%.Among the 14 kinds of allergens,the amount of children with positive dust mites was the highest,followed by milk and cat fur,dog fur and chicken egg protein.Cockroaches,mould,beef and mutton also took a rather high ratio of it.There was no significant difference in the positive rate of allergens between boys and girls(P0.05).In inhalant allergen group,the positive rate of allergens in pre-school children and school-age children were all significantly higher than that of infants(P0.05).In food allergen group,the positive rate of allergens in infants was significantly higher than that in pre-school children and school-age children(P0.05).Among the infants,the positive rate of allergens in food allergen group was significantly higher than that in inhalant allergen group(P0.05);Among the pre-school children and school-age children,the positive rates of allergens in inhalant allergen group were all significantly higher than that in food allergen group(P0.01).Conclusion The main allergen in Quanzhou region is dust mite,followed by milk and cat fur,dog fur and chicken egg protein;There is no significant difference of the positive rate of allergens between boys and girls.The children at different ages have different compositions of allergens.

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Available abstract

Objective To detect specificity serum IgE antibody from children with allergic diseases,then to screen related allergens in order to provide a scientific evidence in the diagnosis and treatment of children with allergic diseases.Methods The specificity serum IgE antibody of 350 children with allergic diseases were detected quantitatively by allergy screen allergens test system.Results The positive rate of 14 kinds of allergens in 350 children with allergic diseases was 57.71%.Among the 14 kinds of allergens,the amount of children with positive dust mites was the highest,followed by milk and cat fur,dog fur and chicken egg protein.Cockroaches,mould,beef and mutton also took a rather high ratio of it.There was no significant difference in the positive rate of allergens between boys and girls(P0.05).In inhalant allergen group,the positive rate of allergens in pre-school children and school-age children were all significantly higher than that of infants(P0.05).In food allergen group,the positive rate of allergens in infants was significantly higher than that in pre-school children and school-age children(P0.05).Among the infants,the positive rate of allergens in food allergen group was significantly higher than that in inhalant allergen group(P0.05);Among the pre-school children and school-age children,the positive rates of allergens in inhalant allergen group were all significantly higher than that in food allergen group(P0.01).Conclusion The main allergen in Quanzhou region is dust mite,followed by milk and cat fur,dog fur and chicken egg protein;There is no significant difference of the positive rate of allergens between boys and girls.The children at different ages have different compositions of allergens.

Key concepts: Allergen, Intoxicative inhalant, Medicine, Immunoglobulin E, Food allergens, Allergy, Immunology, Mite

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