Diagnosis and treatment of chronic obstructive pulmonary disease with secondary pulmonary fungal infections

OBJECTIVE To explore the measures for clinical diagnosis and treatment of chronic obstructive pulmonary disease(COPD) with secondary pulmonary fungal infections and analyze the related risk factors so as to control the disease and reduce the incidence of infections.METHODS The clinical data of 60 cases of COPD patients with secondary pulmonary fungal infections who were enrolled the hospital from Feb 2009 to Feb 2010 were retrospectively analyzed.RESULTS The incidence of secondary pulmonary fungal infections in the COPD patients was directly related to the improper use of broad-spectrum antibiotics or corticosteroids.The Candida albicans,Candida tropicalis,Candida krusei,and Aspergillus were the main species of fungi causing the infections,accounting for 62.5%,15.0%,13.8%,and 8.7%,respectively.Of totally 60 patients,57(95.0%) patients were cured or improved,2 cases were discharged voluntarily,and 1 patient died.CONCLUSION Correct guidance for medication is an important measure to prevent pulmonary infections in the patients with COPD;once the patients are diagnosed as the pulmonary infections,it is necessary to reasonably use antibiotics in accordance with criteria of clinical medication.