The effect of benazepril and felodipine extended release tablet on 24 h ambulatory blood pressure in hypertension patients

Objective To study the efficacy of benazepril and felodipine in hypertension.Methods Sixty two hypertension patients were randomly divided into two groups.Group A(31 cases):benazepril 10 mg at 8 AM.Group B(31 cases):felodipine 5 mg at 8 AM.Both groups were treated for 4 weeks.24 h ambulatory blood pressure was evaluated before and after drug therapy.Results (1)24 hour mean blood pressure was significantly reduced in both groups,but there was no significant difference.The total effective rate was 83.1% for benazepril group,88.2% for felodipine group,but there was no significant difference between two groups(P0.05).(2)The T/P of reduced SP was (62.3±12.8)% for benazepril group,(65.2±13.1)% for felodipine group;The T/P of reduced DP was (68.6±18.3)% for benazepril group,(77.2±12.6)% for felodipine group,but there was no significant difference between two groups (P0.05).Conclusion Both benazepril and felodipine are effective in treatment of hypertension,and T/P is contented.