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2011•Zhongguo fushe weishengRequires access

Effects of Extract of Achynanthis Bidentatae on CFU-S and Hemopoiesis of BFU-E、CFU-E in Irradiated Mice

MA Su-hao

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Abstract

Objective To study the Extract of Achynanthis Bidentatae(ABE) on colony forming unit-spleen(CFU-S)and hemopoiesis of burst forming unit-erythroid(BFU-E)、colony forming unit-erythroid(CFU-E) in Irradiated mice.Methods Using techniques of CFU-S and cell culture of hemopoietic progenitors in vitro,the authors observed the effects of ABE on weight of spleen﹑CFU-S﹑BFU-E and CFU-E.Results It is shown the weight of spleen and the number of CFU-S was increased,but there was no stimulation activity on BFU-E and CFU-E.Conclution ABE may stimulate the proliferation of CFU-S,but there was no effect on differentiation of BFU-E and CFU-E.

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What this paper is about

Objective To study the Extract of Achynanthis Bidentatae(ABE) on colony forming unit-spleen(CFU-S)and hemopoiesis of burst forming unit-erythroid(BFU-E)、colony forming unit-erythroid(CFU-E) in Irradiated mice.Methods Using techniques of CFU-S and cell culture of hemopoietic progenitors in vitro,the authors observed the effects of ABE on weight of spleen﹑CFU-S﹑BFU-E and CFU-E.Results It is shown the weight of spleen and the number of CFU-S was increased,but there was no stimulation activity on BFU-E and CFU-E.Conclution ABE may stimulate the proliferation of CFU-S,but there was no effect on differentiation of BFU-E and CFU-E.

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Available abstract

Objective To study the Extract of Achynanthis Bidentatae(ABE) on colony forming unit-spleen(CFU-S)and hemopoiesis of burst forming unit-erythroid(BFU-E)、colony forming unit-erythroid(CFU-E) in Irradiated mice.Methods Using techniques of CFU-S and cell culture of hemopoietic progenitors in vitro,the authors observed the effects of ABE on weight of spleen﹑CFU-S﹑BFU-E and CFU-E.Results It is shown the weight of spleen and the number of CFU-S was increased,but there was no stimulation activity on BFU-E and CFU-E.Conclution ABE may stimulate the proliferation of CFU-S,but there was no effect on differentiation of BFU-E and CFU-E.

Key concepts: Haematopoiesis, Spleen, Colony-forming unit, CFU-GM, Progenitor cell, Stimulation, Biology, In vitro

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Effects of Extract of Achynanthis Bidentatae on CFU-S and Hemopoiesis of BFU-E、CFU-E in Irradiated Mice — Research Paper | ScholarLens