Infectious distribution and drug resistance analysis of Methicillin-resistant Staphylococcus aureus

Objective To understand the infectious distribution of Methicillin-resistant Staphylococcus aureus(MRSA) and its drug resistance to antibiotics.Methods The identification of staphylococcus aureus(SA) was determined by ATB-Expression,MRSA were identified by disk diffusion method with Cefoxitin,and the K-B method was applied for the drug susceptibility test.Results The isolated rates of MRSA infection were 63.78% in 185 SA.The infectious distribution of MRSA were mainly in neurosurgery,burn and hepatobiliary surgery,general surgery,respiratory medicine department.118 strains of MRSA were resistance to penicillin,ampicillin,piperacillin/tazobactam,cefotaxime,meropenem,ciprofloxacin and erythrocin,and were highly resistance to amikacin and rifampicin.All MRSA were sensitive to vancomycin and teicoplanin.Conclusion MRSA have high and multiple resistant to antimicrobial agents,Vancomycin and teicoplanin were the first drug against MRSA infection.