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Clinical analysis of gene expression spectrum in 11 human urinary bladder transitional cell carcinoma

Lin Gao

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Abstract

Objective To investigate the change of gene expression in human transitional cell carcinoma(TCC).Methods Using DNA chip to detect the mRNA from 11 human transitional cell carcinoma and the normal bladder mucous membrane tissues.Results Controlled by normal bladder mucous membrane tissues, there are obvious up regulation in 102 genes' expression and obvious down regulation in 87 genes' expression in human transitional cell carcinoma tissues.Conclusions Many differential-expressing genes related to bladder transitional cell carcinoma.

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What this paper is about

Objective To investigate the change of gene expression in human transitional cell carcinoma(TCC).Methods Using DNA chip to detect the mRNA from 11 human transitional cell carcinoma and the normal bladder mucous membrane tissues.Results Controlled by normal bladder mucous membrane tissues, there are obvious up regulation in 102 genes' expression and obvious down regulation in 87 genes' expression in human transitional cell carcinoma tissues.Conclusions Many differential-expressing genes related to bladder transitional cell carcinoma.

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Available abstract

Objective To investigate the change of gene expression in human transitional cell carcinoma(TCC).Methods Using DNA chip to detect the mRNA from 11 human transitional cell carcinoma and the normal bladder mucous membrane tissues.Results Controlled by normal bladder mucous membrane tissues, there are obvious up regulation in 102 genes' expression and obvious down regulation in 87 genes' expression in human transitional cell carcinoma tissues.Conclusions Many differential-expressing genes related to bladder transitional cell carcinoma.

Key concepts: Transitional cell carcinoma, Transitional Cell, Urinary bladder, Gene, Gene expression, Cell, Carcinoma, Biology

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