2014•Hainan yixueRequires access

Analysis of influence factors of the long-term prognosis of different schemes on patients with gastric resection in cancer

Wenhu Lu

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Abstract

Objective To explore the influence of the long-term prognosis of the different gastric resection on the patients with middle third gastric cancer. Methods The clinical data of 280 patients with middle third gastric carcinomas underwent radical resection were analyzed. And 194 patients underwent total gastrectomy(TG group) in them, while 86 patients underwent distal gastrectomy(DG group). The five year survival rates were compared between the two groups. By univariate and multivariate analyses, the prognostic factors were evaluated. Results The 5year survival rate of TG group and DG group were 47.6% and 64.3% respectively, and the difference was statistically significant(P0.05). However, patients in group TG had relatively greater tumor and later staging, and tumors located in the lessercurvature side mostly(P0.05). TNM staging prognosis analysis showed that two groups of middle third gastric cancer patients after 5 year survival rate had no significant difference(P0.05); 5 year survival rate of patients with gastric cancer in different central incisal margin also had no statistical significance(P0.05). Multivariate analysis showed that, stomach resection was not the independent prognostic factors of gastric cancer patients(P0.05); and the depth of invasion and TNM stage were the factors affecting the prognosis of gastric cancer patients(P0.05).Conclusion On the premise of radical operation, nearly cutting edge distance does not affect the long-term prognosis of patients with middle gastric cancer. If the middle third gastric carcinoma patients can achieve the requirements of complete eradication, the implementation of distal gastrectomy is feasible.

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Objective To explore the influence of the long-term prognosis of the different gastric resection on the patients with middle third gastric cancer. Methods The clinical data of 280 patients with middle third gastric carcinomas underwent radical resection were analyzed. And 194 patients underwent total gastrectomy(TG group) in them, while 86 patients underwent distal gastrectomy(DG group). The five year survival rates were compared between the two groups. By univariate and multivariate analyses, the prognostic factors were evaluated. Results The 5year survival rate of TG group and DG group were 47.6% and 64.3% respectively, and the difference was statistically significant(P0.05). However, patients in group TG had relatively greater tumor and later staging, and tumors located in the lessercurvature side mostly(P0.05). TNM staging prognosis analysis showed that two groups of middle third gastric cancer patients after 5 year survival rate had no significant difference(P0.05); 5 year survival rate of patients with gastric cancer in different central incisal margin also had no statistical significance(P0.05). Multivariate analysis showed that, stomach resection was not the independent prognostic factors of gastric cancer patients(P0.05); and the depth of invasion and TNM stage were the factors affecting the prognosis of gastric cancer patients(P0.05).Conclusion On the premise of radical operation, nearly cutting edge distance does not affect the long-term prognosis of patients with middle gastric cancer. If the middle third gastric carcinoma patients can achieve the requirements of complete eradication, the implementation of distal gastrectomy is feasible.

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Available abstract

Objective To explore the influence of the long-term prognosis of the different gastric resection on the patients with middle third gastric cancer. Methods The clinical data of 280 patients with middle third gastric carcinomas underwent radical resection were analyzed. And 194 patients underwent total gastrectomy(TG group) in them, while 86 patients underwent distal gastrectomy(DG group). The five year survival rates were compared between the two groups. By univariate and multivariate analyses, the prognostic factors were evaluated. Results The 5year survival rate of TG group and DG group were 47.6% and 64.3% respectively, and the difference was statistically significant(P0.05). However, patients in group TG had relatively greater tumor and later staging, and tumors located in the lessercurvature side mostly(P0.05). TNM staging prognosis analysis showed that two groups of middle third gastric cancer patients after 5 year survival rate had no significant difference(P0.05); 5 year survival rate of patients with gastric cancer in different central incisal margin also had no statistical significance(P0.05). Multivariate analysis showed that, stomach resection was not the independent prognostic factors of gastric cancer patients(P0.05); and the depth of invasion and TNM stage were the factors affecting the prognosis of gastric cancer patients(P0.05).Conclusion On the premise of radical operation, nearly cutting edge distance does not affect the long-term prognosis of patients with middle gastric cancer. If the middle third gastric carcinoma patients can achieve the requirements of complete eradication, the implementation of distal gastrectomy is feasible.

Key concepts: Medicine, Gastrectomy, Cancer, Gastroenterology, Internal medicine, Stomach, Multivariate analysis, Resection margin

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