[The chromatographic-mass spectrometric analysis and detection of anabolic steroids in human urines and metabolic study].
J Zhang, Liu Cs, Bi Hg, Zhang Yz, Ye L, Zhou Th
Abstract
J Zhang, Liu Cs, Bi Hg, Zhang Yz, Ye L, Zhou Th
Abstract
Nineteen anabolic steroids were separately administered to healthy men. Anabolic steroid metabolites were isolated and extracted from the collected urine samples following an integrated procedure. The main metabolic pathways of these drugs were made clear after the investigation by GC-MS. Based on the obtained chromatographic-mass spectrometric data of anabolic steroids, a method for large scale and routine analysis of anabolic steroids was set up.
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Nineteen anabolic steroids were separately administered to healthy men. Anabolic steroid metabolites were isolated and extracted from the collected urine samples following an integrated procedure. The main metabolic pathways of these drugs were made clear after the investigation by GC-MS. Based on the obtained chromatographic-mass spectrometric data of anabolic steroids, a method for large scale and routine analysis of anabolic steroids was set up.
Key concepts: Anabolism, Anabolic steroid, Urine, Chromatography, Chemistry, Anabolic Agents, Gas chromatography–mass spectrometry, Mass spectrometry