Clinical Significance of Assaying Serum Prealbumin in the Patients with Viral Hepatitis

Objective To research into the significance of prealbumin detection in patients with varied viral hepatitis. Methods We assayed the serum prealbumin (S - pA) in 172 patients with varied viral hepatitis and 41 normal persons as the control group. Results S -pA levels were decreased in the acute period or active period of the patients with varied viral hepatitis, compared with the control group. The more severe the patients were, the more significant decrease of the S -pA levels were. The most significant decrease of S -pA level appeared in the patients with severe hepatitis. As the improvement of diseases,the S -pA levels were gradually increased. Conclusion The S - pA level is a sensitive parameter which reflects the damage and the recovery of liver function in the varied viral hepatitis. The S - pA level may reflects the maximum reserve function in the patients with cirrhosis. The dynamical observation of S -pA level may be used to estimate the prognosis of patients with severe hepatitis.