2005•Applied Journal of General PracticeRequires access

Clinical Analysis of 68 Cases with Extrapyramidal Syndrome Caused By Metoclopramide

Zhao Cui-li

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Abstract

Objective To explore the clinical situation and prevention of extrapyramidal syndrome caused by Metoclopramide. Methods From January 1997 to December 2002, 68 patients, including outpatient and inpatients, suffered from extrapyramidal syndrome due to metoclopramide. Once diagnosis was confirmed, metoclopramide were replaced by atropine or 654-2 at once, some patients took artane. Results Among the 68 patients, the extrapyramidal symptoms of 50 patients with spasmodic torticollis and dyskinesia of tongue muscle disappeared in 20 min or 24h. The rest of them were getting better after 40 hours and cured in 3 days. Conclusions Extrapyramidal Syndrome due to Metoclopramide can get better or disappeared after stop taking Metoclopramide immediately and get treatment in time.[

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Objective To explore the clinical situation and prevention of extrapyramidal syndrome caused by Metoclopramide. Methods From January 1997 to December 2002, 68 patients, including outpatient and inpatients, suffered from extrapyramidal syndrome due to metoclopramide. Once diagnosis was confirmed, metoclopramide were replaced by atropine or 654-2 at once, some patients took artane. Results Among the 68 patients, the extrapyramidal symptoms of 50 patients with spasmodic torticollis and dyskinesia of tongue muscle disappeared in 20 min or 24h. The rest of them were getting better after 40 hours and cured in 3 days. Conclusions Extrapyramidal Syndrome due to Metoclopramide can get better or disappeared after stop taking Metoclopramide immediately and get treatment in time.[

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Available abstract

Objective To explore the clinical situation and prevention of extrapyramidal syndrome caused by Metoclopramide. Methods From January 1997 to December 2002, 68 patients, including outpatient and inpatients, suffered from extrapyramidal syndrome due to metoclopramide. Once diagnosis was confirmed, metoclopramide were replaced by atropine or 654-2 at once, some patients took artane. Results Among the 68 patients, the extrapyramidal symptoms of 50 patients with spasmodic torticollis and dyskinesia of tongue muscle disappeared in 20 min or 24h. The rest of them were getting better after 40 hours and cured in 3 days. Conclusions Extrapyramidal Syndrome due to Metoclopramide can get better or disappeared after stop taking Metoclopramide immediately and get treatment in time.[

Key concepts: Metoclopramide, Medicine, Extrapyramidal symptoms, Dyskinesia, Anesthesia, Extrapyramidal disorder, Sulfisoxazole, Internal medicine

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