[A clinical study of reflux oesophagites].

OBJECTIVE: To study the incidence and role of acid and bile reflux in gastroesophageal reflux disease (GERD). METHODS: Fifty two patients with reflux symptoms were studied. All of them were performed endoscopy received acid and bile reflux monitoring. RESULTS: Fifty two patients received acid and bile reflux monitoring, 42 patients had reflux with the main type of double-reflux (both acid and bile reflux) which was 59.5% (25/42), and with the type of the single-reflux which was 40.5% (17/42). Among single-reflux, the acid reflux was the main type about 76.4% (13/17); Among double-reflux, the degree of acid reflux was more severe, than did bile reflux; The percent of reflux oesophagites join the double-reflux patients was significant high than that in single-acid-reflux patients (P < 0.05); There was a liner correlation between acid reflux index either the frequency or the severity of reflux symptoms. CONCLUSIONS: Double-reflux was the main type of reflux in GERD, and acid reflux was the main type among double-reflux and single-reflux. There may be a synergistic effect between acid and bile reflux. Acid reflux was the main factor for reflux symptoms.