2003•Foreign Medical Sciences Section of Maternal and Child HealthRequires access
Lysophosphatidic acid and ovarian cancer
Yang Yu
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Abstract
lysophosphatidic acid (LPA) is a bioactive phospholipid, which exhibits kinds of biological activities by binding to and activating members of the Edg subfamily of G protein coupled receptors, which link to multiple G proteins to elicit cellular responses. Recently researches indicated that abnormalities in LPA metabolism and its function may be associated with the growth, invasion and metastases of ovarian cancer. LPA is of a potential value in early diagnosis of ovarian cancer.