2013China Medicine and PharmacyRequires access

Podocyte damage and the research progress of membranous nephropathy

Song Aifen

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Abstract

Membranous nephropathy is a common primary glomerular disease.The pathological features is based on the deposition of immune complexes diffuse glomerular visceral epithelial cells and basement membrane thickening with spikes.Its pathogenesis is complicated.In recent years,the in-depth study of markers of podocytes confirmed that podocytes is closely related to the generation of abnormal proteinuria.This thesis overviewed the progress on podocyte abnormalities of membranous nephropathy development.

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Membranous nephropathy is a common primary glomerular disease.The pathological features is based on the deposition of immune complexes diffuse glomerular visceral epithelial cells and basement membrane thickening with spikes.Its pathogenesis is complicated.In recent years,the in-depth study of markers of podocytes confirmed that podocytes is closely related to the generation of abnormal proteinuria.This thesis overviewed the progress on podocyte abnormalities of membranous nephropathy development.

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Available abstract

Membranous nephropathy is a common primary glomerular disease.The pathological features is based on the deposition of immune complexes diffuse glomerular visceral epithelial cells and basement membrane thickening with spikes.Its pathogenesis is complicated.In recent years,the in-depth study of markers of podocytes confirmed that podocytes is closely related to the generation of abnormal proteinuria.This thesis overviewed the progress on podocyte abnormalities of membranous nephropathy development.

Key concepts: Membranous nephropathy, Podocyte, Medicine, Glomerular basement membrane, Pathogenesis, Thickening, Pathological, Proteinuria

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