Development of quality of life questionnaire for cancer patients QLQ-52 and the evaluation of questionnaire's quality

Objective:To develop a self-assessed questionnaire of quality of life QLQ-52 suitable for the people of Chinese culture background.Methods:We surveyed 133 cases of cancer patients to evaluate the quality of QLQ-52 by reliability, validity, responsiveness and feasibility to reflect the quality of the questionnaire.Results:The new questionnaire composed of 52 entries was formed by 6 domains which were physical, psychological, independent, social and environmental relations, spirit support and satisfactory degree. The patients' reliability Pearson correlation was 0.334(P0.01),split-half reliability was 0.9242, Cronbach's coefficient was 0.9404. The content validity was 94.00%, construct validity showed that percentage of cumulative is 0.87, The Pearson coefficient of criterionrelated validity was 0.574(P0.01). The responsiveness was evaluated by the difference of QOL of pre/during and post treatment which was significant (P0.05). The feasibility was evaluated by completed rate, average completed time and the median time which were 93.66%, 14.3 minutes, and 12 minutes.Conclusion:The reliability, validity, responsiveness and feasibility of QLQ-52 are practical in medical clinic. The QLQ-52 may be used widely by the medical clinic in China to evaluate the QOL of cancer patients.