2003•Journal of Guangdong Medical CollegeRequires access

Relationship between mean corpuscular volume,mean corpuscular hemoglobin of umbilical blood and thalassemia

Luo Gui

Abstract

Objective:To study the relationship between mean corpuscular volume(MCV),mean corpuscular hemoglobin(MCH) of umbilical blood and thalassemia.Methods:MCV and MCH,Hb Bart's and alpha thalassemia 1 gene were determined by automatic analyzer,electrophoresis and gap PCR respectively in 35 neonates with thalassemia and 46 normal newborns.Results:MCV and MCH in patients were significantly lower than those in normal controls( P 0.01).Conclusion:MCV and MCH of umbilical blood might be important clues to the diagnosis of thalassemia.

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Key concepts: Mean corpuscular volume, Thalassemia, Mean corpuscular hemoglobin, Mean corpuscular hemoglobin concentration, Hemoglobin, Medicine, Internal medicine