Clinical Observation of Painless Abortion Induced by Propofol-Lidocaine-Ketamine

Objective:To compare anesthesia effects of painless abortion with five different kinds of anesthesia methods and to explore the feasibility of propofol-Lidocaine-Ketamine used for painless abortion.Methods: 200 early pregnant women were devided randomly into five groups:(Ⅰ)propofol alone,(Ⅱ) lidocaine-propofol,(Ⅲ)fentanyl-propofol,(Ⅳ) ketamine-propofol,(Ⅴ)ketamine-lidocaine-propofol.The consumption of propofol,recovery time,departure time,BP,HR,sPO_2 at per 2 min before and after anesthesia,as well as the adverse reaction of operation were observed and recorded.Results: Among five groups of patients,the consumption in group(Ⅰ)(Ⅱ) was higher than that in other three groups(P0.01),the levels of BP、HR、sPO_2 of patients was significantly decreased in groupⅠ,Ⅱ and Ⅲ(P0.05),the decrease of group Ⅲ was the most significant(P0.01).Recovery time and departure time in group IV was longer than that in the other four groups(P0.05).About the incidence of local injection pain,groupⅠ was higher than groupⅢ,and groupⅢ higher than group Ⅳ;group Ⅳ higher than GroupⅡ;but local injection pain didn't occur in group Ⅴ.Conclusion: Propotol-Lidocaine-Ketamine used for painless abortion is safer and more reliable.