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Advances in Synthesis of Pyrazole and Pyrazole Derivatives

Kai Zhao, Xian‐Hong Yin

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Abstract

The main methods of synthesis of pyrazole and pyrazole derivatives were reviewed in this paper.The former included the reactions of 1,3-diketone compounds and hydrazine,the reactions of alkyl diazo-compounds and alkenoene compounds,the reactions of ethyl acetoacetate and hydrazine,the reactions of acrylonitrile or malononitrile compounds and hydrazine,the reactions of alkenone compounds and hydrazine.The synthetic technologies included solid-synthesis and micro wave-assistant synthesis.

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What this paper is about

The main methods of synthesis of pyrazole and pyrazole derivatives were reviewed in this paper.The former included the reactions of 1,3-diketone compounds and hydrazine,the reactions of alkyl diazo-compounds and alkenoene compounds,the reactions of ethyl acetoacetate and hydrazine,the reactions of acrylonitrile or malononitrile compounds and hydrazine,the reactions of alkenone compounds and hydrazine.The synthetic technologies included solid-synthesis and micro wave-assistant synthesis.

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Available abstract

The main methods of synthesis of pyrazole and pyrazole derivatives were reviewed in this paper.The former included the reactions of 1,3-diketone compounds and hydrazine,the reactions of alkyl diazo-compounds and alkenoene compounds,the reactions of ethyl acetoacetate and hydrazine,the reactions of acrylonitrile or malononitrile compounds and hydrazine,the reactions of alkenone compounds and hydrazine.The synthetic technologies included solid-synthesis and micro wave-assistant synthesis.

Key concepts: Chemistry, Pyrazole, Hydrazine (antidepressant), Ethyl acetoacetate, Malononitrile, Acrylonitrile, Organic chemistry, Alkyl

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