Advances in Synthesis of Pyrazole and Pyrazole Derivatives
Kai Zhao, Xian‐Hong Yin
Abstract
Kai Zhao, Xian‐Hong Yin
Abstract
The main methods of synthesis of pyrazole and pyrazole derivatives were reviewed in this paper.The former included the reactions of 1,3-diketone compounds and hydrazine,the reactions of alkyl diazo-compounds and alkenoene compounds,the reactions of ethyl acetoacetate and hydrazine,the reactions of acrylonitrile or malononitrile compounds and hydrazine,the reactions of alkenone compounds and hydrazine.The synthetic technologies included solid-synthesis and micro wave-assistant synthesis.
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The main methods of synthesis of pyrazole and pyrazole derivatives were reviewed in this paper.The former included the reactions of 1,3-diketone compounds and hydrazine,the reactions of alkyl diazo-compounds and alkenoene compounds,the reactions of ethyl acetoacetate and hydrazine,the reactions of acrylonitrile or malononitrile compounds and hydrazine,the reactions of alkenone compounds and hydrazine.The synthetic technologies included solid-synthesis and micro wave-assistant synthesis.
Key concepts: Chemistry, Pyrazole, Hydrazine (antidepressant), Ethyl acetoacetate, Malononitrile, Acrylonitrile, Organic chemistry, Alkyl