The diagnosis value of bone marrow imaging in aplastic Anemia

Aim: To evaluate the clinical value of bone marrow imaging in the diagnosis of aplastic anemia (AA).Methods: We studied retrospectively 63 adults with hematological diseases by bone marrow imaging and divided them into 2 groups including AA( n =24) and non-AA ( n =39)groups. All cases were diagnosed and proved bone marrow smear both/or biopsy methods. We evaluate the sensitivity and specificity of bone marrow imaging.Results: According to the bone marrow imaging results, we defined grade 2 of marrow activities as normal. The sensitivity was 90 0% in severe aplastic anemia (SAA) and 78 6% in chronic aplastic anemia (CAA). Sensitivity and specificity was 83 3% and 61 5%.Conclusions:Whole body bone marrow imaging is a safe and sensitive method to identify AA . It helps clinical physicians to identify the distribution and condition of the functional marrow.