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2007•Zhejiang Medical JournalRequires access

The differential diagnosis value of CRP in benign and malignant pleural effusions

Wang Xuefe

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Abstract

Objective To evaluate the significance of C-reactive protein (CRP) in the differential diagnosis of tuberculosis pleural effusions and malignant pleural effusions. Methods The levels of CRP in 25 tuberculosis pleural effusions and 20 malignant pleural effusions were measured by immunodiffusion. Results The CRP levels in patients with tuberculosis pleural effusions were higher than those with malignant pleural effusions (39.6±15.3mg/L vs 9.1±2.9 mg/L, t=5.267, P0.01). Taking 20.0mg/L as cut-off level, the sensitivity for diagnosis of tuberculosis pleural effusions was 76.0%, specificity was 90.0%. Conclusion The CRP levels in pleural effusions are of clinically diagnostic value in distinguishing tuberculosis from malignant pleural effusions.

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Objective To evaluate the significance of C-reactive protein (CRP) in the differential diagnosis of tuberculosis pleural effusions and malignant pleural effusions. Methods The levels of CRP in 25 tuberculosis pleural effusions and 20 malignant pleural effusions were measured by immunodiffusion. Results The CRP levels in patients with tuberculosis pleural effusions were higher than those with malignant pleural effusions (39.6±15.3mg/L vs 9.1±2.9 mg/L, t=5.267, P0.01). Taking 20.0mg/L as cut-off level, the sensitivity for diagnosis of tuberculosis pleural effusions was 76.0%, specificity was 90.0%. Conclusion The CRP levels in pleural effusions are of clinically diagnostic value in distinguishing tuberculosis from malignant pleural effusions.

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Available abstract

Objective To evaluate the significance of C-reactive protein (CRP) in the differential diagnosis of tuberculosis pleural effusions and malignant pleural effusions. Methods The levels of CRP in 25 tuberculosis pleural effusions and 20 malignant pleural effusions were measured by immunodiffusion. Results The CRP levels in patients with tuberculosis pleural effusions were higher than those with malignant pleural effusions (39.6±15.3mg/L vs 9.1±2.9 mg/L, t=5.267, P0.01). Taking 20.0mg/L as cut-off level, the sensitivity for diagnosis of tuberculosis pleural effusions was 76.0%, specificity was 90.0%. Conclusion The CRP levels in pleural effusions are of clinically diagnostic value in distinguishing tuberculosis from malignant pleural effusions.

Key concepts: Medicine, Tuberculosis, Differential diagnosis, Pleural effusion, Pleural fluid, Malignant pleural effusion, Internal medicine, Pathology

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