Effect of Different Lodine Concentration of Contrast Media in the Enhancement of kidney with Multislice CT

Objective:To study the effect of contrast enhancement of kidney with contrast media containing iodine for 300 or 400mg I/ml in MSCT.Methods:Totally 40 patients with suspected kidney diseases were randomly assigned into two groups,20 patients for each group.Group A received contrast media containing 300mg iodine/ml(1.5ml/kg of body weight),whereas group B received the same agent yet containing 400mg iodine/ml(1ml/kg of body weight),the injection rate was 3ml/s.MSCT was undertaken at 18s,30s,80s and 3~5min after starting of injection.The CT value(HU) of abdominal aorta,renal arteries,veins,cortex,medulla and renal pelvis of bilateral kidney as well as renal lesion were measured to observe the degree of enhancement in different phases.Results:For group B,at 18s and 30s,high iodine concentration contrast led to greater enhancement in blood vessels and normal renal structures than group A,with significant statistical difference(P0.01).At 80s,high iodine concentration used in group B led to greater enhancement in renal arteries,renal veins,renal medulla than group A,with significant statistical difference(P0.01).At 3 to 5min,enhancement was greater in renal veins and renal pelvis,with significant statistical difference as well(P0.01).Conclusion:High iodine concentration contrast media improves contrast enhancement of renal vessels,the overall volume of contrast media used could be reduced.For MSCT of kidney,it is reasonable to use high iodine concentration contrast media,and to perform the CT scanning at 30s and 3min to 5min after starting of injection.