2011•Linchuang gandanbing zazhiRequires access
Model for end-stage liver disease to predict survival in patients with chronic severe hepatitis B
Liu We
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Abstract
Objective To evaluate the value of model for end-stage liver disease(MELD)scoring system in predicting the prognosis of patients with chronic severe hepatitis B receiving plasma exchange.Methods Total serum bilirubin,international normalized ratio and creatinine were determined pre-treatment and post-treatment in 112 patients with chronic severe hepatitis B who were treated with plasma exchange.The patients were divided into three groups according to MELD score.The mortality rate within three months post-treatment were compared in three groups.Results In 63 cases with MELD score less then 30,19% patients died;in 34 cases with MELD score between 30 and 40,58.8% died;and in 15 cases with MELD score more than 40,none of them survived.The mortality rates among the three groups were significantly different(P0.05).Conclusion MELD scoring system is useful in predicting the prognosis of patients with chronic severe hepatitis B treated with plasma exchange.