ScholarLens Back to search
2007•Laboratory Medicine and ClinicRequires access

Diagnostic value of combined detection of serum IV-C, HA and LN concentrations for hepatic fibrosis in chronic hepatic patients

Zhang Xijia

Open publisher page 0 citations

Abstract

Objective To investigate changes of serum levels of collagen type Ⅳ(Ⅳ-C), hyaluronic acid (HA) and laminin (LN), as well as their relationship with hepatic fibrosis in chronic hepatic patients.Methods Serum levels of Ⅳ-C, HA and LN were measured with ELISA in 128 patients with HBV infection of various types.Results Serum levels of Ⅳ-C, HA and LN were significantly higher in patients with HBV infection of various types than those in normal controls (P0.01).Conclusion Serum levels of Ⅳ-C, HA and LN could reflect the degree of hepatic fibrosis easily.

About this research paper

What this paper is about

Objective To investigate changes of serum levels of collagen type Ⅳ(Ⅳ-C), hyaluronic acid (HA) and laminin (LN), as well as their relationship with hepatic fibrosis in chronic hepatic patients.Methods Serum levels of Ⅳ-C, HA and LN were measured with ELISA in 128 patients with HBV infection of various types.Results Serum levels of Ⅳ-C, HA and LN were significantly higher in patients with HBV infection of various types than those in normal controls (P0.01).Conclusion Serum levels of Ⅳ-C, HA and LN could reflect the degree of hepatic fibrosis easily.

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Objective To investigate changes of serum levels of collagen type Ⅳ(Ⅳ-C), hyaluronic acid (HA) and laminin (LN), as well as their relationship with hepatic fibrosis in chronic hepatic patients.Methods Serum levels of Ⅳ-C, HA and LN were measured with ELISA in 128 patients with HBV infection of various types.Results Serum levels of Ⅳ-C, HA and LN were significantly higher in patients with HBV infection of various types than those in normal controls (P0.01).Conclusion Serum levels of Ⅳ-C, HA and LN could reflect the degree of hepatic fibrosis easily.

Key concepts: Hepatic fibrosis, Hyaluronic acid, Laminin, Gastroenterology, Medicine, Internal medicine, Type IV collagen, Chronic hepatic

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
Diagnostic value of combined detection of serum IV-C, HA and LN concentrations for hepatic fibrosis in chronic hepatic patients — Research Paper | ScholarLens