The correlation between CT perfusion imaging and CTP score for evaluation of liver reserve function in river cirrhosis patients

Objective To explore the clinical significance of CT perfusion imaging (CTPI)and the relationship between Child-Turcotte-Pugh (CTP) score and CTPI for evaluation of liver reserve function in patients with liver cirrhosis. Methods Thirty patients with liver cirrhosis and 30 healthy subjects as control group were included in this study.CTP score and CT perfusion imaging were carried out in all participants,and perfusion parameters of CTPI including hepatic portal perfusion (HPP),hepatic arterial perfusion(HAP),total liver perfusion(TLP)and hepatic perfusion index (HPI)were calculated.The correlation between perfusion parameters of CTPI and CTP score was evaluated with linea corralative analysis. Results The HPP[(0.4958±0.2313) vs (0.9356±0.2679)ml/min·ml,P=0.000]and the TLP[(0.8437±0.3242) vs (1.1326±0.3720) ml/min·ml,P=0.022] were lower in liver cirrhosis patients than those in control group.There were negative correlations between the CTP score and HPP(r =-0.793,P=0.000)and between the CTP score and TLP(r=-0.815,P=0.021). Conclusions Compared with CTP score system,CT perfusion parameters can reflect the blood perfusion of liver in liver cirrhosis patients and have some guidances to evaluate the reserve function of liver.