Zhenhua Huang
Abstract
Ximelagatran is a direct thrombin inhibitor and is able to inhibit both free and clot-bound thrombin with the advantages of strong inhibition effect,wide therapeutic window,reversible inhibition and short response time.It plays an important role in the treatment of atrial fibrillation.
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Ximelagatran is a direct thrombin inhibitor and is able to inhibit both free and clot-bound thrombin with the advantages of strong inhibition effect,wide therapeutic window,reversible inhibition and short response time.It plays an important role in the treatment of atrial fibrillation.
Key concepts: Ximelagatran, Direct thrombin inhibitor, Atrial fibrillation, Thrombin, Discovery and development of direct thrombin inhibitors, Anticoagulant, Pharmacology, Antithrombins