A contrastive study on concurrent chemoradiotherapy and sequential chemoradiotherapy for advanced cervical cancer

Objective:To explore the clinical effect of concurrent chemoradiotherapy and sequential chemoradiotherapy for advanced cervical cancer.Methods:86 cases with advanced cervical cancer were randomly divided into concurrent chemoradiotherapy group(46 cases) and sequential chemoradiotherapy group(40 cases).The clinical effect,survival rate and complications were analyzed in two group.Results:The local contral were 91.3% and 87.5% in concurrent chemoradiotherapy group and sequential chemoradiotherapy group respectively with significant difference(P0.05);the total 4 survival rate were 84.8% and 70.0% in the two group with significant difference(P0.05);the pelvic recurrence and distant metastasis were much lower in concurrent chemoradiotherapy group than that of sequential chemoradiotherapy group(P0.05).Bone marrow inhibition and reaction of digestive tract were the major complications,but the patients could bear the sufferings.Conclusion:Compared with sequential chemoradiotherapy,concurrent chemoradiotherapy for advanced cervical cancer can improve the total 4 survival rate and lower the pelvic recurrence and distant metastasis with complications tolerated.