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2007•Xinjiang Yike Daxue xuebaoRequires access

Study of quality control on Tangzhiyi tablets

Haiying Zhang

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Abstract

Objective: To establish quality control of Tangzhiyi tablets. Methods: astraglionych, coptidis rhizoma, chinese hawthorn were identified by thin layer chromatograph (TLC). The contents of berberine hydrochloride were determined by high performance liquid chromatograph (HPLC). Results: Astraglionych, coptidis rhizoma, and Chinese hawthorn could be indentified by TLC, berberine hydrochloride showed a good linear relationship at a range of 0.006 24～0.031 20 mg/ml, r=0.999 2, The average recovery rate was 98.89%. Conclusion: The methods are accurate and reliable, and can be used for the quality control of Tangzhiyi tablets effectively.

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What this paper is about

Objective: To establish quality control of Tangzhiyi tablets. Methods: astraglionych, coptidis rhizoma, chinese hawthorn were identified by thin layer chromatograph (TLC). The contents of berberine hydrochloride were determined by high performance liquid chromatograph (HPLC). Results: Astraglionych, coptidis rhizoma, and Chinese hawthorn could be indentified by TLC, berberine hydrochloride showed a good linear relationship at a range of 0.006 24～0.031 20 mg/ml, r=0.999 2, The average recovery rate was 98.89%. Conclusion: The methods are accurate and reliable, and can be used for the quality control of Tangzhiyi tablets effectively.

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Available abstract

Objective: To establish quality control of Tangzhiyi tablets. Methods: astraglionych, coptidis rhizoma, chinese hawthorn were identified by thin layer chromatograph (TLC). The contents of berberine hydrochloride were determined by high performance liquid chromatograph (HPLC). Results: Astraglionych, coptidis rhizoma, and Chinese hawthorn could be indentified by TLC, berberine hydrochloride showed a good linear relationship at a range of 0.006 24～0.031 20 mg/ml, r=0.999 2, The average recovery rate was 98.89%. Conclusion: The methods are accurate and reliable, and can be used for the quality control of Tangzhiyi tablets effectively.

Key concepts: Berberine hydrochloride, Chromatography, High-performance liquid chromatography, Berberine, Quality standard, Recovery rate, Linear relationship, Chemistry

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