2008•China Practical MedicineRequires access

A analysis on the effect of two kinds of triple therapies in gastropathy relevant to Helicobacter pylori

BU Xiang-yi

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Abstract

Objective To evaluate the effect of two kinds of triple therapies in gastropathy relevant to Helicobacter pylori.Methods 136 patients with gastropathy relevant to Helicobacter pylori,included peptic ulcer 85 cases and chronic gastritis 51 cases.Peptic ulcer patients were assigned to 2 groups randomly:the Omerazole group with 42 cases and the CBS group with 43 cases,Chronic gastritis patients were also assigned to 2 groups at random:the Omerazole group with 26 cases and the CBS group with 25 cases.After one week of triple therapy for Peptic ulcer patients,treated with Omerazole and CBS for 6 weeks,Chronic gastritis received triple therapies for one week.After stopped therapy 4 weeks,every patient was rechecked with gastroscope in order to observe the Hp removing rate and ulcer cure rate.Results For the peptic ulcer patients,The HP removing rate of the Omerazole group and the CBS group were 95.2%and 93.0%respectively,there was no diffierence between them(P0.05),The ulcer cure ratio of two groups were 95.2%and 48.8%respectively,with marked difference(P0.01).For chronic gastritis patients,the HP removing rates were 92.3%and 88.0%respectively,there was no marked difference(P0.05).Conclusion The Omerazole plans to treat peptic ulcer patients with postive HP has marked effect,However the CBS plans to treat gastritic patients with postive HP has the positive curative effect and the cheaper cost.

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What this paper is about

Objective To evaluate the effect of two kinds of triple therapies in gastropathy relevant to Helicobacter pylori.Methods 136 patients with gastropathy relevant to Helicobacter pylori,included peptic ulcer 85 cases and chronic gastritis 51 cases.Peptic ulcer patients were assigned to 2 groups randomly:the Omerazole group with 42 cases and the CBS group with 43 cases,Chronic gastritis patients were also assigned to 2 groups at random:the Omerazole group with 26 cases and the CBS group with 25 cases.After one week of triple therapy for Peptic ulcer patients,treated with Omerazole and CBS for 6 weeks,Chronic gastritis received triple therapies for one week.After stopped therapy 4 weeks,every patient was rechecked with gastroscope in order to observe the Hp removing rate and ulcer cure rate.Results For the peptic ulcer patients,The HP removing rate of the Omerazole group and the CBS group were 95.2%and 93.0%respectively,there was no diffierence between them(P0.05),The ulcer cure ratio of two groups were 95.2%and 48.8%respectively,with marked difference(P0.01).For chronic gastritis patients,the HP removing rates were 92.3%and 88.0%respectively,there was no marked difference(P0.05).Conclusion The Omerazole plans to treat peptic ulcer patients with postive HP has marked effect,However the CBS plans to treat gastritic patients with postive HP has the positive curative effect and the cheaper cost.

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Available abstract

Objective To evaluate the effect of two kinds of triple therapies in gastropathy relevant to Helicobacter pylori.Methods 136 patients with gastropathy relevant to Helicobacter pylori,included peptic ulcer 85 cases and chronic gastritis 51 cases.Peptic ulcer patients were assigned to 2 groups randomly:the Omerazole group with 42 cases and the CBS group with 43 cases,Chronic gastritis patients were also assigned to 2 groups at random:the Omerazole group with 26 cases and the CBS group with 25 cases.After one week of triple therapy for Peptic ulcer patients,treated with Omerazole and CBS for 6 weeks,Chronic gastritis received triple therapies for one week.After stopped therapy 4 weeks,every patient was rechecked with gastroscope in order to observe the Hp removing rate and ulcer cure rate.Results For the peptic ulcer patients,The HP removing rate of the Omerazole group and the CBS group were 95.2%and 93.0%respectively,there was no diffierence between them(P0.05),The ulcer cure ratio of two groups were 95.2%and 48.8%respectively,with marked difference(P0.01).For chronic gastritis patients,the HP removing rates were 92.3%and 88.0%respectively,there was no marked difference(P0.05).Conclusion The Omerazole plans to treat peptic ulcer patients with postive HP has marked effect,However the CBS plans to treat gastritic patients with postive HP has the positive curative effect and the cheaper cost.

Key concepts: Medicine, Helicobacter pylori, Gastroenterology, Internal medicine, Gastritis, Chronic gastritis, Peptic ulcer, Peptic

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