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Effect of Xinanling on Blood Rheology of Model Rats with Acute Blood Stasis

Fang Tai-hui

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Abstract

OBJECTIVE To observe the effect of Xinanling on rheology,platelet aggregation and clotting time of model rats with acute stasis.METHOD Ice water stimulation method was used to make blood stasis model used to detect the main rheology indexes,and ADP was used as the revulsive to observe its effect on in vitro platelet aggregation.RESULT ①Xinanling could reduce the maximum platelet aggregation of rats;②Xinanling could reduce the clotting time of rats;③Xinanling could reduce the viscosity of rats;and ④Xinanling could inhibit the platelet aggregation ability and increase the red cell metamorphotic ability of rats.CONCLUSION Xinanling has the actions of inhibiting platelet aggregation,prolonging clotting time and improving rheology.

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What this paper is about

OBJECTIVE To observe the effect of Xinanling on rheology,platelet aggregation and clotting time of model rats with acute stasis.METHOD Ice water stimulation method was used to make blood stasis model used to detect the main rheology indexes,and ADP was used as the revulsive to observe its effect on in vitro platelet aggregation.RESULT ①Xinanling could reduce the maximum platelet aggregation of rats;②Xinanling could reduce the clotting time of rats;③Xinanling could reduce the viscosity of rats;and ④Xinanling could inhibit the platelet aggregation ability and increase the red cell metamorphotic ability of rats.CONCLUSION Xinanling has the actions of inhibiting platelet aggregation,prolonging clotting time and improving rheology.

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Available abstract

OBJECTIVE To observe the effect of Xinanling on rheology,platelet aggregation and clotting time of model rats with acute stasis.METHOD Ice water stimulation method was used to make blood stasis model used to detect the main rheology indexes,and ADP was used as the revulsive to observe its effect on in vitro platelet aggregation.RESULT ①Xinanling could reduce the maximum platelet aggregation of rats;②Xinanling could reduce the clotting time of rats;③Xinanling could reduce the viscosity of rats;and ④Xinanling could inhibit the platelet aggregation ability and increase the red cell metamorphotic ability of rats.CONCLUSION Xinanling has the actions of inhibiting platelet aggregation,prolonging clotting time and improving rheology.

Key concepts: Blood stasis, Blood clotting, Rheology, Platelet aggregation, Platelet, Clotting time, Chemistry, Stimulation

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