Cryptochrome: A Light-dependent Magnetoreceptor

Insects and birds are able of detecting magnetic field to sense direction,but how this is done remained not quite understood. Accumulating evidence suggested that a protein located in the retina of migratory birds,known as cryptochrome,was a key sensory molecule. A radical pair generated when cryptochrome absorbs light is known to process photochemical transformation and detect magnetic field. In human,cryptochrome participates in the transcription-translation feedback loops of circadian rhythms.When transfected into fruit fly,it alters the sensing of magnetic field. Here,we summarize the recent progresses on cryptochrome studies,as well as the underlining mechanism related to light-dependent magnetoreception. The implication and perspective for future research is discussed.