A Molecularly Imprinted Electrochemical Sensor of Dopamine

A novel sensitive molecularly imprinted electrochemical sensor has been developed for selective detection of dopamine by combination of polyaniline,multiwalled carbon nanotube and gold nanoparticle-silk fibroin composite.The molecularly imprinted polymer(MIP) was synthesized using dopamine as the template molecule,tetraethyl orthosilicate and triethoxyphenylsilane as the functional monomers.Under pH=7.0 and the template-monomer ratio of 1∶5,the current response had a linear relationship with the concentration of dopamine in the range of 5.0×10-8 mol/L～9×10-6 mol/L,with a limit of detection 1.02×10-8 mol/L.The relative standard deviation(RSD) of the repeated experiments was 5.4%.