Study on combination with enteral and parenteral nutritional supplement in patients after pancreaticoduodenectomy

Objective Clinical studies have demonstrated that early postoperative enteral nutrition(EN) is questionable in its execution.Post-pancreaticoduodenectomy patients tend to suffer easily from nausea,abdominal distention,and diarrhoea,while submitted to postoperative EN.In this pilot study,we tried to select a more suitable nutritional supplement mode in post-pancreaticoduodenectomy patients.Methods Thirty-six patients were performed pancereaticoduodnectomy between Sep 2007 and Mar 2010,and were divided into 2 modes of postoperative nutritional supplement in a prospective single-centered study.Eighteen patients received only EN and 18 patients received EN combined with parenteral nutrition(EN+PN group).Results There were no difference in clinical characteristics and postoperative morbidity between the 2 groups.The rale of discontinuation of the EN was significantly higher in the 1st group,and the duration of enteral feeding was significantly longer in the 2nd or EN+PN group.There was no difference in the frequency of nutrition-related index between the 2 groups.Conclusions The EN +PN mode is more suitable for nutritional support of the patients with pancreaticoduodenectomy.