Mycoplasma and drug resistance analysis among patients with nongonococcal urethritis

Objective To find out the status about detection and drug resistance of ureaplasma urealyticum(Uu) and mycoplasma hominis(Mh) among patients with nongonococcal urethritis(NGU).Methods A total of 853 specimens from the nongonococcal urethritis patients were collected,cultured and tested for drug sensitivity.Results In 853 samples of nongonococcal urethritis patients,494 samples cultured of mycoplasma were positive,and the positive rate was 57.9%.Among these cases,320 samples(37.5 %) were Uu positive,72 samples(8.4%) Mh positive,102 samples(12.0%) Uu+Mh positive.In the drug sensitive test,Uu and Mh were most sensitive to Josamycin and Doxycycline respectively.To Erythromycin and Roxithromycin,they had the highest level of drug resistance respectively.Uu+Mh were most sensitive to Mincycline and most resistant to Roxithromycin.Conclusion The major mycoplasma of the nongonococcal urethritis were Uu.Josamycin,Doxycycline,Mincycline and Clarithromycin may be preferred drugs selected to treat mycoplasma infection.The clinical therapy of mycoplasma infection ought to choose the appropriate antibiotics based on the results of the drug sensitive test of the laboratory.