2000•The Practical Journal of CancerRequires access

Prognostic Analysis of 1091 Cases of Lung Cancer

Han Xiang-w

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Abstract

Objective To explore the prognostic factors of lung cancer.Methods 1 091 cases of primary lung cancer were analysed in age、clinical stage、pathology and therapy.Product-limit method was used to calculate the survival rate,its significance was tested by logrank test.Results The overall 1、3、5 year survival rate was 29.6%、9.4%、5.0% respectively.The 5-year survival rate of 40~50 years old patients was higher than those of others(P0.05).The 5-year survival rate was 13.2% for squamous carcinoma, 9.5% for adenocarcinoma,0 for small cell carcinoma(P0.05).The 5-year survival rate was 17.0% in stage Ⅰ,9.5% in stage Ⅱ,1.9% in stage Ⅲa,0 in stage Ⅲb and Ⅳ(P0.05).The 5-year survival rate was 18.1% in treatment with operation,0.02%,without operation.The 5-year survival rate was 25.7% in lobectomy and 10.8% in pneumonectomy(P0.05).The 5-year survival rate for surgery alone(22.1%) was higher than those for operation plus radiotherapy and/or chemotherapy,but there was not significant difference(P0.05).The 5-year survival rate was 2.4% for radiotherapy and chemotherapy group and 0 for other treatment without operation(P0.05).Conclusion Age、pathology、clinical stage and different treatment were important factors affecting prognosis of lung cancer.

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What this paper is about

Objective To explore the prognostic factors of lung cancer.Methods 1 091 cases of primary lung cancer were analysed in age、clinical stage、pathology and therapy.Product-limit method was used to calculate the survival rate,its significance was tested by logrank test.Results The overall 1、3、5 year survival rate was 29.6%、9.4%、5.0% respectively.The 5-year survival rate of 40~50 years old patients was higher than those of others(P0.05).The 5-year survival rate was 13.2% for squamous carcinoma, 9.5% for adenocarcinoma,0 for small cell carcinoma(P0.05).The 5-year survival rate was 17.0% in stage Ⅰ,9.5% in stage Ⅱ,1.9% in stage Ⅲa,0 in stage Ⅲb and Ⅳ(P0.05).The 5-year survival rate was 18.1% in treatment with operation,0.02%,without operation.The 5-year survival rate was 25.7% in lobectomy and 10.8% in pneumonectomy(P0.05).The 5-year survival rate for surgery alone(22.1%) was higher than those for operation plus radiotherapy and/or chemotherapy,but there was not significant difference(P0.05).The 5-year survival rate was 2.4% for radiotherapy and chemotherapy group and 0 for other treatment without operation(P0.05).Conclusion Age、pathology、clinical stage and different treatment were important factors affecting prognosis of lung cancer.

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Available abstract

Objective To explore the prognostic factors of lung cancer.Methods 1 091 cases of primary lung cancer were analysed in age、clinical stage、pathology and therapy.Product-limit method was used to calculate the survival rate,its significance was tested by logrank test.Results The overall 1、3、5 year survival rate was 29.6%、9.4%、5.0% respectively.The 5-year survival rate of 40~50 years old patients was higher than those of others(P0.05).The 5-year survival rate was 13.2% for squamous carcinoma, 9.5% for adenocarcinoma,0 for small cell carcinoma(P0.05).The 5-year survival rate was 17.0% in stage Ⅰ,9.5% in stage Ⅱ,1.9% in stage Ⅲa,0 in stage Ⅲb and Ⅳ(P0.05).The 5-year survival rate was 18.1% in treatment with operation,0.02%,without operation.The 5-year survival rate was 25.7% in lobectomy and 10.8% in pneumonectomy(P0.05).The 5-year survival rate for surgery alone(22.1%) was higher than those for operation plus radiotherapy and/or chemotherapy,but there was not significant difference(P0.05).The 5-year survival rate was 2.4% for radiotherapy and chemotherapy group and 0 for other treatment without operation(P0.05).Conclusion Age、pathology、clinical stage and different treatment were important factors affecting prognosis of lung cancer.

Key concepts: Medicine, Lung cancer, Survival rate, Stage (stratigraphy), Radiation therapy, Adenocarcinoma, Pneumonectomy, Internal medicine

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