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Optimization of the Extraction Technology of Catalpol from Rehmannia glutinosa Libosch by Orthogonal Design

Wei Zhong-min

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Abstract

Objective To explore an optimum extraction technology of Catalpol from Rehmannia glutinosa Libosch.Methods Using catalpol as the index,the effects of alcohol concentration,extraction time,solvent amount and extraction degree on extraction technology were evaluated by orthogonal design.Results The superior technology of catalpol was as follows: 95% alcohol,1 hour,12 fold solvent and extracted 2 times.Conclusion The optimum extraction process is stable and accurate,and it is suitable for extraction of catalpol from Rehmannia glutinosa Libosch.

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What this paper is about

Objective To explore an optimum extraction technology of Catalpol from Rehmannia glutinosa Libosch.Methods Using catalpol as the index,the effects of alcohol concentration,extraction time,solvent amount and extraction degree on extraction technology were evaluated by orthogonal design.Results The superior technology of catalpol was as follows: 95% alcohol,1 hour,12 fold solvent and extracted 2 times.Conclusion The optimum extraction process is stable and accurate,and it is suitable for extraction of catalpol from Rehmannia glutinosa Libosch.

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Available abstract

Objective To explore an optimum extraction technology of Catalpol from Rehmannia glutinosa Libosch.Methods Using catalpol as the index,the effects of alcohol concentration,extraction time,solvent amount and extraction degree on extraction technology were evaluated by orthogonal design.Results The superior technology of catalpol was as follows: 95% alcohol,1 hour,12 fold solvent and extracted 2 times.Conclusion The optimum extraction process is stable and accurate,and it is suitable for extraction of catalpol from Rehmannia glutinosa Libosch.

Key concepts: Catalpol, Rehmannia glutinosa, Extraction (chemistry), Chromatography, Chemistry, Mathematics, Traditional medicine, Botany

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