Efficacy contrast of different antiplatelet therapy in patients after percutaneous coronary intervention

Objective To investigate the efficacy of different antiplatelet therapy in patients after percutaneous coronary intervention(PCI).Methods 132 patients with coronary heart disease were randomly assigned to double antiplatelet group and triple antiplatelet group after underwent PCI operation.The patients in double antiplatelet group were asked to take Aspirin 100 mg/d long term and Clopidogrel 75 mg/d for one year,while triple antiplatelet group took Cilostazol 100 mg/d for six month in addition.Follow-up was to investigate the difference of major adverse cardiac and cerebrovascular events(MACCE),as well as platelet aggregation rate between the 2 groups.Results Compared to double antiplatelet group,MACCE of triple antiplatelet group decreased(P 0.05).The difference between two groups of MLD and LL was observed 6 months after operation(P 0.05),and there was significant deviation of RR in 2 groups.Conclusion For patients with coronary heart disease after PCI operation,the use of Cilostazol besides Aspirin and Clopidogrel can prevent thrombosis,the late lumen loss and effectively decrease restenosis rate.