Clinical Study on the Correlation between Vaginal Bleeding during Early Pregnancy and Preterm Delivery

Objective To explore the correlation between vaginal bleeding during early pregnancy and preterm delivery.Methods The differences of distribution were evaluated between normal pregnant and premature delivery patients based on pregnant patients.The correlation between vaginal bleeding during early pregnancy and preterm delivery was investigated based on the stratified analysis.Results There were 295 subjects with preterm delivery and the ratio of vaginal bleeding during pregnancy was 25.01%.There were no statistical differences of reproductive history and work during pregnancy between groups of normal subjects and preterm delivery(P0.05).There were statistical differences of maternal age,body index and vaginal bleeding in groups(P0.05).Compared to subjects without bleeding,the vaginal bleeding in early pregnancy was associated with a 1.06 to 1.81 fold increased risk of preterm delivery.The correlation between vaginal bleeding in early pregnancy and spontaneous preterm labor was highest(P=0.002).Compared to subjects without bleeding,the vaginal bleeding in early pregnancy was associated with a 1.11 to 1.97 fold increased risk of mild preterm delivery(P=0.008).Conclusion The vaginal bleeding in early pregnancy is associated with an increased risk of preterm delivery.Especially,the ratios of spontaneous preterm labor and mild preterm delivery rise up.