Relationship between nodular goiter and lymphocytic thyroiditis

Objective To explore the significance of nodular goiter with lymphocytic thyroiditis. Methods 548 cases of nodular goiter, 35 cases of thyroid adenoma and 17 cases of thyroid carcinoma were collected. Their incidence rate and lesion features with lymphocytic thyroiditis were observed. Results Nodular goiters with lymphocytic thyroiditis were 25 4% (139/548), among which focal lymphocytic thyroiditis were 24 3% (133/548), Hosimoto's thyroiditis were 1 1% (6/548). Thyroid adenomas had no any case with lymphocytic thyroiditis (0/35), and thyroid carcinomas with focal lymphocytic thyroiditis were 64 7%. Conclusions The incidence of nodular goiter with lymphocytic thyroiditis, especially focal lymphocytic thyroiditis is higher,which indicate that nodular goiter may be relative to autoimmunization in some degree. Otherwise, whether focal lymphocytic thyroiditis exists or not, can be one of the points to distinguish adenoma from nodular goiter.