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A Semi-quantitatively Test Method for the Preservative Efficacy and the Analysis of Test Results

XU Zhian

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Abstract

A semi-quantitatively microbial challenge test method(koko test) is introduced in this article,7 strains of bacteria,1 strain of yeast,2 strains of mould are chosen as representative challenging microorganisms,the preservative efficacy of 3 cosemetic products are estimated by this method,the preservative system is: 0.0095% methylisothiazolinone(MIT),0.2% methylparaben(MP),0.1% propylparaben(PP).Confirming with the test method of USP and CTFA,the koko test method showed the advantage of credible results and convenient operation within 28d experiments.

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What this paper is about

A semi-quantitatively microbial challenge test method(koko test) is introduced in this article,7 strains of bacteria,1 strain of yeast,2 strains of mould are chosen as representative challenging microorganisms,the preservative efficacy of 3 cosemetic products are estimated by this method,the preservative system is: 0.0095% methylisothiazolinone(MIT),0.2% methylparaben(MP),0.1% propylparaben(PP).Confirming with the test method of USP and CTFA,the koko test method showed the advantage of credible results and convenient operation within 28d experiments.

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Available abstract

A semi-quantitatively microbial challenge test method(koko test) is introduced in this article,7 strains of bacteria,1 strain of yeast,2 strains of mould are chosen as representative challenging microorganisms,the preservative efficacy of 3 cosemetic products are estimated by this method,the preservative system is: 0.0095% methylisothiazolinone(MIT),0.2% methylparaben(MP),0.1% propylparaben(PP).Confirming with the test method of USP and CTFA,the koko test method showed the advantage of credible results and convenient operation within 28d experiments.

Key concepts: Methylparaben, Propylparaben, Preservative, Chemistry, Test method, Test (biology), Yeast, Chromatography

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