Influence of cigarette smoking on sperm DNA integrity

Objective To explore the impact of smoking on sperm DNA integrity.Methods 120 infertile men were divided into 3 groups according to smoking quantity and duration.The group A:daily smoking 10 cigarettes and smoking age ≤1 year; the group B:daily smoking 10-20 cigarettes and smoking age 5-10 years; the group C:daily smoking ≥20 cigarettes and smoking age ≥10 years.35 cases of healthy men having child were recruited as control in the study.The parameters of their semen and sperm DFI were detected.Results The sperm motility in the infertile smoker group was significantly lower than that in the infertile non-smoker group and sperm DFI was significantly increased; in the group C,sperm motility was significantly lower than that in the group B and group A,while the DFI was significantly increased.Conclusion Smoking can influence the sperm DNA integrity and seriously affect the quality of semen.