Clinical analysis of pathogenic bracteria strain in lower respiratory tract of 156 patients with tuberculosis

Objective To investigate the characteristics of distribution and drug resistance of pathogenic bracteria strain in lower respiratory tract of patients with tuberculosis.Method The results of microbial culture of 156 patients with tuberculosis in Tuberculosis hospital in Bin Zhou from June 2008 to June 2009 were analysed retrospectively.Result 186 strains of pathogenic bacteria were cultured in 156 patients.Gram negative bacillus accounted for 61.5%.Gram negative pole coccus accounted for 22.6%.Fungi accounted for 16.1%.The main bacteria were Pseudomonas aeruginosa,Pneumonia,White clay,Staphylococcus aureus,and Candida albicans.Susceptibility test indicated that the majority of pathogenic bacteria were significant resistance to not beta-lactamase-producing eniyme inhibitors of penicillin and the first and second,some third-generation cephalosporin,but for carbon eniyme of antibiotic sensitivity rate was higher.Vancomycin for staphylococcus aureus sensitive rate was 100%.Conclusion Tuberculosis with lower respiratory infections and drug resistance are serious.So in patients with tuberculosis infection clinical antibiotic treatment should based on sensitivity tests.