Diagnostic value of ECG-gated early post-exercise ~(99m)Tc-MIBI myocardial perfusion imaging in coronary artery disease

Objective:To study and compare the diagnostic value of ECG-gated and non ECG-gated early post-exercise stress ~ 99m Tc-MIBI myocardial perfusion imaging (MPI) in coronary heart disease(CHD).Method:Two hundred and fifteen known or suspected CHD patients who had undergone coronary angiography and ECG-gated MPI within one month in our hospital were enrolled and values of diagnostic sensitivity, specificity were gained and compared among ETT, non ECG-gated MPI and ECG-gated MPI.Result:When angiographic diameter stenosis ≥50% is the diagnostic standard of CHD, the sensitivity of ETT, non ECG-gated MPI and G-MPI are 58.0%(94/162),88.3%(143/162),90.7%(147/162) ,respectively;the specificity are 67.9%(36/53),79.2%(42/53),88.7%(47/53) , respectively. ETT, non ECG-gated MPI and ECG-gated MPI have incremental diagnostic value in order with the latter two significantly better than ETT (both P0.01). The specificity of non ECG-gated MPI was better than that of ETT (P0.05), and less than ECG-gated MPI (P0.05), while the specificity of ECG-gated MPI is superior to ETT significantly (P0.01).Conclusion:In CHD diagnoses,ECG-gated MPI is significantly better than ETT,and possibly better than non ECG-gated MPI.